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Description
FSHR Recombinant Rabbit mAb (SDT-2269-36)Product Specification Host Rabbit Antigen FSHR Synonyms Follicle stimulating hormone receptor; FSH R; Follitropin receptor; LGR1 Immunogen Synthetic Peptide Location Cell membrane Accession P23945 Clone Number SDT 2269 36 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC, IF Reactivity Hu, Ms, Rt Positive Sample SK OV 3, OVCAR 3, DU 145, PC 3, mouse kidney, rat testis Purification Protein A Concentration 0. 5 mg ml Conjugation
Product Specification
| Host | Rabbit |
| Antigen | FSHR |
| Synonyms | Follicle-stimulating hormone receptor; FSH-R; Follitropin receptor; LGR1 |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | P23945 |
| Clone Number | SDT-2269-36 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, ICC, IF |
| Reactivity | Hu, Ms, Rt |
| Positive Sample | SK-OV-3, OVCAR-3, DU 145, PC-3, mouse kidney, rat testis |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000-1:5000 | Hu, Ms, Rt |
| IHC-P | 1:1000 | Hu, Ms, Rt |
| ICC | 1:500 | Hu |
| IF | 1:100 | Ms |
Background
The follicle-stimulating hormone receptor (FSHR) is a 695-amino-acid, seven-transmembrane G-protein-coupled receptor expressed primarily on granulosa and Sertoli cells; upon binding FSH it activates the Gs/adenylyl cyclase/cAMP/PKA cascade to regulate steroidogenesis, gametogenesis, and reproductive tract differentiation, with naturally occurring activating or inactivating mutations causing disorders such as ovarian hyperstimulation syndrome or hypergonadotropic hypogonadism, and its extracellular domain being the target of modern infertility therapies and male contraceptive development.
Shipping Notes
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Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
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